Pegfilgrastim versus filgrastim

Due to a longer half-life and slower elimination rate than filgrastim, pegfilgrastim requires less frequent dosing than filgrastim; however, pegfilgrastim has

Related drugs Filgrastim Lenograstim Lipegfilgrastim Pegfilgrastim.

Use of pegfilgrastim vs short-acting G-CSF. Clinical trial data suggest a similar efficacy and safety profile with pegfilgrastim and 11 days filgrastim. 1 If 11 days filgrastim is not utilized, pegfilgrastim should be given in preference to a reduced duration of daily filgrastim (consensus reached (91%); evidence level I).

filgrastim (Granix) and sargramostim (Leukine). Filgrastim and pegfilgrastim products are recombinant granulocyte colony- stimulating

Although prospective, randomized clinical trials of filgrastim versus depot pegfilgrastim demonstrated biologic equivalency, retrospective studies in patients with solid tumors suggest the use of pegfilgrastim results in reduced rates of admission for neutropenic fever.

This article reports the randomized study of pegfilgrastim versus filgrastim in children and young adults with newly diagnosed sarcoma. The results encompass the primary clinical outcome (number of days of severe neutropenia) and toxicity profile, as well as laboratory correlates including pharmacokinetic analysis of pegfilgrastim and filgrastim, pharmacodynamic correlation with absolute

Pegfilgrastim per Cycle Versus Daily Filgrastim as an. Adjunct to Chemotherapy in Subjects With High-risk. Stage II or Stage III/IV Breast

Filgrastim Firmagon Floxuridine Fludarabine Fludara Pegfilgrastim Pegfilgrastim On-Pro Peginterferon Alfa-2b Pemazyre

A trend towards a lower incidence of febrile neutropenia was noted across all cycles with pegfilgrastim compared with filgrastim (13% versus 20%, respectively). A single fixed dose of pegfilgrastim was as safe and well tolerated as standard daily filgrastim.