Fluoxetine pharmacokinetics

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Actual: Pharmacokinetic Parameters of the SSRIs Escitalopram Citalopram Fluoxetine Paroxetine Sertraline Half-life half-life observed for fluoxetine.
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Pharmacokinetic research indicates that enzymes implicated in fluoxetine metabolism exhibit similar affinities for fluoxetine enantiomers (R-fluoxetine and S-fluoxetine); the only exception to this is the CYP2C9 enzyme which stereo-selectively metabolizes R-fluoxetine over S-fluoxetine.

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Sertraline and citalopram show linear pharmacokinetics while fluoxetine, fluvoxamine, and paroxetine show nonlinear pharmacokinetics . The SSRIs are metabolized by the cytochrome P450 system in the liver.

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20 mg once daily. Pharmacokinetics for fluoxetine. Consider the long half-life of fluoxetine when adjusting dosage (or in overdosage)

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by AC Altamura 2024 Cited by 388In contrast with its effect on the pharmacokinetics of other antidepressants, age does not affect fluoxetine pharmacokinetics. This finding together with

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Objectives: The aim of the present study was to evaluate the influence of Fluoxetine (antidepressant drug) on pharmacokinetic and

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Pharmacokinetics: Fluoxetine has a long half-life: - fluoxetine 2-3 days. - Nor-fluoxetine 7-9 days. Changes in dosage would therefore not be

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Fluoxetine (Prozac), Fluvoxamine (Luvox), and Paroxetine (Paxil). It highlights their pharmacokinetic and pharmacodynamic properties

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does not affect fluoxetine pharmacokinetics. This finding together with the better tolerability profile of fluoxetine (compared with tricyclic

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Pharmacokinetics for fluoxetine. Consider the long half-life of fluoxetine when adjusting dosage (or in overdosage). Unlicensed use.

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