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No, don't substitute any over-the-counter products, like aspirin or omeprazole (Prilosec), for Yosprala (aspirin / omeprazole) without speaking with your provider first. Over-the-counter omeprazole (Prilosec) only comes as a delayed (extended)-release form, while the omeprazole in this combination medication is in an immediate-release form.

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over-the-counter preparations. Many over-the-counter cough and cold Prednisone in equivalent doses may be substituted if

No, don't substitute any over-the-counter products, like aspirin or omeprazole (Prilosec), for Yosprala (aspirin / omeprazole) without speaking with your provider first. Over-the-counter omeprazole (Prilosec) only comes as a delayed (extended)-release form, while the omeprazole in this combination medication is in an immediate-release form.