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LD50. 235mg/kg. Mouse. IP. LD50 40 mg/kg. Mouse. Oral. LD50. 600mg/kg. Sodium chloride. Mouse. Intravenous. LD50 156mg/kg. HYDROCHLORIC ACID.
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The LD50 for oral diphenhydramine in dogs has not been studied; however, the Benadryl (Diphenhydramine Hydrochloride) for Injection [Material Safety Data
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Pharmacokinetic/ Toxicokinetic Property ; Toxicity LD50, 4000.0, mg/kg ; Toxicity LD50, 2024.0, mg/kg ; Toxicity LD50, .0, mg/kg ; Eliminate Route, 60.0, %
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30 minutes. The duration of In rats, the oral LD50, intraperitoneal LD50, and subcutaneous LD50 is 2600 mg/kg, 800 mg/kg, and 4600 mg/kg, respectively.
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In rats, the oral LD50, intraperitoneal LD50, and subcutaneous LD50 is 2600 mg/kg, 800 mg/kg, and 4600 mg/kg, respectively. The Lowest published toxic dose (
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5 minutes, and the peak effect is reached within 30 minutes. In rats, the oral LD50, intraperitoneal LD50, and subcutaneous LD50 is 2600 mg/kg, 800 mg/kg, and
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10 to 90%. The oral In rats, the oral LD50, intraperitoneal LD50, and subcutaneous LD50 is 2600 mg/kg, 800 mg/kg, and 4600 mg/kg, respectively.
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Rat Oral LD50 404 mg/kg Mouse Oral LD50 900 mg/kg Hydroxyzine hydrochloride Rat Oral LD50 840 mg/kg Sucrose Mouse Inhalation LC50 4h 39 g/m3 Mouse IP LD50 81 mg/kg Ethanol Rat IP LD50 160 mg/kg Rat Oral LD50 29.7 g/kg Mouse IV LD50 137 mg/kg
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The oral LD50 is 400 mg/kg and the subcutaneous LD50 is 100 mg/kg in mice.
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