Treatment for Chronic Phase CML. Three drugs are now available for treating CML in its chronic phase: Treatment for Accelerated Phase CML Treatment for Blast
Targeted therapies are typically used first in CML treatment. These are drugs that attack a specific part of the cancer cell to kill it. In the case of CML
Chronic Myeloid Leukemia (CML) is a type of cancer that In the later lines of CML treatment, newer drugs that go beyond TKIs
Still, these drugs don't always work, and CML can become resistant to TKIs over time. Scientists continue to look for new drugs to treat CML, especially CML that no longer responds to TKIs. In some people, CML cells develop a change in the BCR-ABL oncogene known as a T315I mutation, which makes them resistant to many of the TKI drugs used today
In CML, TKIs target the abnormal BCR-ABL1 protein that causes uncontrolled CML cell growth and block its function, causing the CML cells to die. Four TKI drugs are approved as initial therapy (first-line treatment) for chronic phase CML.
Targeted therapy drugs commonly used for CML Imatinib (Gleevec) was the first TKI developed to treat CML. Almost everyone diagnosed with CML will be given
International CML Foundation to improve the outcomes for patients with CML globally.
New Drugs for CML; Update on the French and German Interferon combination studies; Age-adjusted treatment in CML- Elderly and Pregnancy report for young CML
CML Specialist. . Drugs used in the treatment of CML are quite powerful and it is important that you inform your doctor of any medications you are taking
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