Thionamide drugs

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Actual: There are 3 mainstays of treatment: thionamide drugs, radioiodine, and thyroid surgery. Thionamide drugs include propylthiouracil (PTU) and methimazole and reduce the production of thyroid hormone by acting as preferential substrates for thyroid peroxidase.
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Interactions. Drug-Drug. Additive bone marrow depression with thioamide, thionamide IODINE, IODIDE antithyroid, antithyroidal metOLazone.

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Thionamide drugs may also have a direct effect on the immune response within the thyroid gland of patients with Graves' disease, where the drugs are concentrated. The mechanism of action of thionamides involves blocking thyroid hormone synthesis by inhibiting the oxidation of iodide or iodotyrosyl.

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Anti-thyroid drugs, such carbimazole (a thionamide), are normally used for the first episode of Graves' disease. Thionamides, however, are not indicated for

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Hyperthyroidism is treated with antithyroid drugs called thionamides. Thionamides treat an overactive thyroid by blocking your thyroid gland from making new

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Antithyroid drugs. The thionamide antithyroid drugs carbimazole and propylthiouracil decrease thyroid hormone synthesis by inhibiting thyroid peroxidase.

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Anti-thyroid drugs, such carbimazole (a thionamide), are normally used for the first episode of Graves' disease. Thionamides, however, are not indicated for

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Antithyroid drugs are drugs that either decrease thyroid hormone synthesis (thionamides) or thyroid hormone release (iodides).

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Among the drugs that are more commonly associated with agranulocytosis are clozapine, the thionamides (antithyroid drugs), sulfasalazine, and

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Thioamides (or rarely thionamides) are major drugs for treatment of thyrotoxicosis and hyperthyroidism. Some alternative antithyroid drugs

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