Drugs that cause necrosis

There are a number of drugs that cause direct toxicity to the renal tubules (acute tubular necrosis) - eg, aminoglycosides, amphotericin and ciclosporin. Drugs

by J Beecker Cited by 64 Skin-popping, or injecting drugs into the skin, can induce extensive ulcerative necrosis. Krokodil is believed to cause more extensive skin necrosis

Biologic drugs, such as tumour necrosis factor inhibitors (TNFi), work by reducing or eliminating certain proteins that cause inflammation.

Drug-induced tubulointerstitial nephritis and acute tubular necrosis are common, and are often cause by antibiotics or non-steroidal anti-inflammatory drugs.

ACMT Toxicology Visual Pearl: Needle to Necrosis - Xylazine, when mixed with illicit opioids, can cause severe skin necrosis. Drugs: A

What causes avascular necrosis? Bone fractures or disease that prevent blood flow to bone tissue causes avascular necrosis. About 20% of avascular necrosis cases happen without an obvious cause. Known causes of avascular necrosis are: Traumatic avascular necrosis: This can happen after you break a bone or dislocate a joint.

materials are thought to cause abscess and necrosis Nicolau syndrome caused by non-steroidal anti-inflammatory drugs: Systematic literature

Triggers Directly caused by the drug, e.g. lamotrigine, progesterone, or chemotherapeutics causing tumor necrosis Possible side effect of stimulants and

Podofilox (podophyllotoxin) is a patient-applied antimitotic drug that causes wart necrosis. Podofilox solution (using a cotton swab) or