Amlodipine and statins interaction

Some medications may interact with statins by decreasing the effectiveness of the statin. Norvasc (amlodipine); Lanoxin (digoxin); Cardizem (

reported, but none with a simvastatin-amlodipine interaction. [16, 17] gerous interactions of some statins (simvastatin) with drugs.

amlodipine which were not observed with simvastatin 20 mg plus amlodipine. Statins: interactions, and updated advice for atorvastatin

Statin and drug interactions by likely mechanism: statins The drug combinations included (1) simvastatin, amlodipine, and atorvastatin

Examples of statins include atorvastatin (Lipitor) amlodipine (Norvasc); ranolazine (Ranexa). Another important drug interaction occurs between statins

3. Change to an alternative statin. pravastatin, fluvastatin or rosuvastatin do not interact with amlodipine; atorvastatin (20mg or 40mg daily) is an option if a more potent statin is needed. The risk of an interaction with amlodipine is much lower with atorvastatin than simvastatin; 4.

Pharmacokinetic data suggest a minor increase in statin exposure with coadministration of amlodipine and lovastatin or simvastatin, and combination therapy may be considered. There is no evidence of significant interaction when amlodipine is coadministered with other statins.

by BS Wiggins 2024 Cited by 283There is no evidence of significant interaction when amlodipine is coadministered with other statins. Although evidence for statin interactions with

These are the three statins to remember when it comes to drug interactions with amlodipine but there are even more subtleties that than. When amlodipine is taken together with simvastatin or lovastatin, it inhibits the metabolism of the statins, leading to higher-than-intended levels of statins in the bloodstream.