Deflazacort vs prednisone

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Actual: Efficacy and safety of deflazacort vs prednisone and placebo for Duchenne muscular dystrophy. Objective: To assess safety and efficacy of deflazacort (DFZ) and prednisone (PRED) vs placebo in DMD. Methods: This phase III, double-blind, randomized, placebo-controlled, multicenter study evaluated muscle strength among 196 boys aged 5 ‑ 15 years
4.8 rating 2025-04-24
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by DW Hammers 2024 Cited by 27Glucocorticoids, specifically prednisone/prednisolone and deflazacort Efficacy and safety of deflazacort vs prednisone and placebo for Duchenne muscular

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Prednisone is combined with Deflazacort. Deflazacort: therapeutic index, relative potency and equivalent doses versus other corticosteroids.

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Deflazacort vs. Prednisone: 5 Differences Between These Muscular Dystrophy Treatments Deflazacort and prednisone are corticosteroids with similar uses and side effects. Learn about the differences between deflazacort and prednisone with GoodRx.

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In a 52-week trial of deflazacort at 0.9 or 1.2 mg / kg / day compared with prednisone at 0.75 mg / kg / day, boys treated with deflazacort had slightly higher muscle strength than boys treated with prednisone with no difference between the high vs low dose of deflazacort. 11 A large natural history study (n=340) reaffirmed that treatment over

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by M Guglieri 2024 Cited by 71Visual Abstract. Efficacy and Safety of Vamorolone vs Placebo Treatment with oral corticosteroids (prednisone, deflazacort) delays

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Accueil; Deflazacort versus prednisone in premenopausal women with chronic arthritis. Deflazacort versus prednisone in premenopausal women with chronic

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by PB Shieh 2024 Cited by 57Deflazacort versus Prednisone/Prednisolone: ACT DMD Trial Analysis Efficacy and safety of deflazacort vs prednisone and placebo for.

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Deflazacort and prednisone were equally effective in improving motor function and functional performance at 1 year. At 9 months, the average weight increase vs baseline was 5% in the deflazacort group and 18% in the prednisone group (p 0.005).

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Weight gain was greater at 1 year and at 18 months in the prednisone group compared with the deflazacort group (increase in weight for prednisone vs deflazacort was 21.65% vs 12.95% at 1 year [p = 0.001] and 32.04% vs 21.67% at 18 months [p = 0.046]).

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