Cyanide toxicity nitroprusside

Cyanide toxicity is a rare complication of sodium nitroprusside that can be difficult to diagnose in critically ill patients. We describe a case of cyanide toxicity after cardiac surgery that presented as lactic acidosis after discontinuation of nitroprusside.

(B) CYANIDE TOXICITY: Sodium nitroprusside metabolism produces dose-related cyanide, which can be lethal. A patient's ability to buffer cyanide

Infants are particularly susceptible to cyanide toxicity. If signs of cyanide toxicity appear: Discontinue sodium nitroprusside infusion. Consult Poisons

Overdosage of nitroprusside can be manifested as excessive hypotension or cyanide toxicity or as thiocyanate toxicity. In moderate cases

An early manifestation of cyanide toxicity is increasing dosage requirements to maintain blood pressure control. Metabolic acidosis may not be evident for more than an hour after toxic cyanide levels accumulate. If cyanide toxicity develops, discontinue sodium nitroprusside, and consider specific treatment of cyanide toxicity [see Overdosage ].

Page 18. Nitroprusside Induced Cyanide Toxicity. Molecule: 5 cyanide radicals, gradually released, occasionally produce cyanide or thiocyanate toxicity.

Overdosage of nitroprusside can be manifested as excessive hypotension or cyanide toxicity or as thiocyanate toxicity. In moderate cases

SODIUM NITROPRUSSIDE STRENGTHENED CYANIDE TOXICITY WARNING has been adopted by Abbott and Hoffmann-La Roche, marketers of sodium nitroprusside under the

An early manifestation of cyanide toxicity is increasing dosage requirements to maintain blood pressure control. Metabolic acidosis may not be evident for more than an hour after toxic cyanide levels accumulate. If cyanide toxicity develops, discontinue sodium nitroprusside, and consider specific treatment of cyanide toxicity [see Overdosage