Buccally administered drugs

Sublingual and buccal medications are administered by placing them in the mouth, either under the tongue (sublingual) or between the gum and the cheek (buccal).

The most common drug given by this route is nitroglycerin. To administer a buccal medication place the medication between the patient's cheek and gum. The drug

rectal diazepam (iv preparation administered rectally), approx 0.5 mg/kg. (n=165) vs buccal midazolam (iv preparation administered buccally), approx 0.5 mg/kg.

by WA Caudill Cited by 6drug is administered buccally is not known. The purpose of this study is to recovery period following buccal administration. Also, pain following

Enzyme inhibitors co-administered in buccal drug delivery systems could improve the buccal absorption of drugs, particularly of peptides/proteins. Enzyme inhibitors, such as aprotinin, bestatin, puromycin and some bile salts act by changing the activities of buccal enzymes, altering their conformation and/or impairing enzyme-drug interaction.

If it is particularly difficult to get the syringe into one buccal cavity, then administer the whole dose over a duration of 4 – 5 seconds into the other buccal

A sublingual tablet formulation with an enhanced acceptability has been successfully developed where the drug is released and undergoes fast absorption into the systemic circulation [81]. How is buccal medication administered? Buccal: To give a drug buccally, insert it between the patient s cheek and gum (as shown below).

In addition, investigation into details of absorption of buccally administered IN DDAVP would be valuable, potentially including measuring serum concentrations of the drug. In summary, the IN formulation of DDAVP administered buccally is a safe and effective treatment for neurogenic DI in infancy.

The drug may be administered SC, IM, IV, or buccally; buccal administration is the preferred route for chronic pain management.3. Buccal (transmucosal)