Allopurinol half life

The half-life of allopurinol is 1 to 2 hours, and oxypurinol is about 15 hours.

Allopurinol is metabolized in the liver and has a 1 3 hour half-life, while oxypurinol is excreted in the urine and has a 12 17 hour half-life. Therefore, allopurinol can be dosed once daily, with lower dosage requirements in patients with renal insufficiency, as the half-life of oxypurinol increases as the creatinine clearance decreases.

Thai or Korean descent), allopurinol should not be started unless there are no other filtration rate, allopurinol has a plasma half-life of about 1 to

Allopurinol Colchicine. Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. 27 hours.

Drug Febuxosta Allopurinol Half-life 1.3 to 15.8 hours Allopurinol: 1 to 3 hours.

Allopurinol is metabolized in the liver and has a 1 3 hour half-life, while oxypurinol is excreted in the urine and has a 12 17 hour half-life. Therefore, allopurinol can be dosed once daily, with lower dosage requirements in patients with renal insufficiency, as the half-life of oxypurinol increases as the creatinine clearance decreases.

Allopurinol has a plasma half-life of about 1 to 2 hours. Oxipurinol is a less potent inhibitor of xanthine oxidase than allopurinol, but the plasma half

Allopurinol prolongs half-life of oral anticoagulants; allopurinol increases substitute for professional advice, diagnosis or treatment. Lybrate is

allopurinol can inhibit the metabolism of dicoumarol, at least in some individuals. In contrast, allopurinol did not affect the half-life of racemic warfarin.