These effects will primarily be based on how drugs act at the receptors of the autonomic system neurochemistry. The signaling molecules of the nervous system
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Q. How do anticholinergics affect dementia risk? A. Anticholinergic drugs act by blocking acetylcholine, a chemical involved in nervous system functions. When the drugs block these functions in
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Readers reasonably expect verisimilitude.
Characters who act like they are aliens from another solar system rather than humans are only to be expected when they actually are aliens from another solar system.
When no one the reader has ever met would act even remotely similar to the way the characters act then the reader loses connection to the story.