Fluconazole and warfarin

☑️@fluconazole_and_warf · 5232 subscribers · Content 18+ 🔞
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Actual: Fluconazole, ↑. Hold warfarin x1 for single dose. Expect % warfarin dose reduction for extended course. ; Fluoroquinolones, ↑. Not always clinically
4.7 rating 2025-04-26
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The published fluconazole PBPK model was integrated with the S-warfarin model to evaluate the inhibitory effect of fluconazole on S-warfarin metabolism. 43 Inhibition of CYP2C9 and CYP3A4 by fluconazole was established using a noncompetitive inhibition process.

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by EV Hersh Cited by 2avoidance of fluconazole is recommended in patients taking warfarin fluconazole and metronidazole can inhibit warfarin's metabolism and lead to

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Treatment. APO-FLUCONAZOLE (fluconazole) is indicated for the treatment of: receiving fluconazole concurrently with warfarin. Dose adjustments

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Amiodarone. Increase. Decreases warfarin metabolism ; Antifungal agents. Increase. Fluconazole, ketoconazole, and miconazole (vaginal) decrease warfarin

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Fluconazole, ↑. Hold warfarin x1 for single dose. Expect % warfarin dose reduction for extended course. ; Fluoroquinolones, ↑. Not always clinically

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Perioperative management of warfarin is covered in the BC Guideline Warfarin Therapy – Management During Invasive o fluconazole o itraconazole.

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Fluconazole, ↑. Hold warfarin x1 for single dose. Expect % warfarin dose reduction for extended course. ; Fluoroquinolones, ↑. Not always clinically

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A common antifungal medication, fluconazole (Diflucan), can interact with many medications, like atorvastatin and warfarin. Explore more fluconazole interactions with GoodRx.

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Fluconazole/warfarin interaction. Sublingual and retropharyngeal haematoma following warfarin overdose and interaction: case report. Erschienen in: Reactions

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