Midazolam half life

half-life of midazolam ranges from 1.5–2.5 hours. The elimination half-life of the metabolite is shorter than 1 hour; therefore after midazolam administration

Level of sedation. Contraindications Known hypersensitivity to midazolam. Precautions. In preterm infants, especially in extreme preterm, midazolam half-life is

half-life of midazolam by 1.5 to 1.8-fold. Clarithromycin increased the plasma concentrations of intravenous midazolam by up to 2.5-fold associated with an

mild effect on the terminal half-life of oral midazolam tablet, increasing by 30%, indicates half-life of midazolam was increased by 41%. Various medicinal

Lorazepam (Ativan), Midazolam (Versed) - IV, Midazolam (Versed) - PO - Due to differences in half-life, active metabolites, and drug

Both midazolam and lorazepam may be used for sedation by continuous intravenous infusion. Theoretically, midazolam is preferable for its short elimination half-life but, in practice, during long-term infusion the half-life is extended and, with impairment of hepatic and renal function, the half-life of midazolam is further extended.

Lorazepam (Ativan), Midazolam (Versed) - IV, Midazolam (Versed) - PO - Due to differences in half-life, active metabolites, and drug

Short-acting – median half-life of 1-12 hours Midazolam, triazolam Intermediate-acting – median half-life of hours Alprazolam

Lorazepam (Ativan), Midazolam (Versed) - IV, Midazolam (Versed) - PO Varying durations of action - Due to differences in half-life