The cumulative exposure of EXPAREL in these studies is well in excess of the proposed maximum single-dose exposure that is intended in humans.
The recommended dose of EXPAREL for local infiltration in adults is up to a maximum dose of 266 mg, and is based on the following factors.
The maximum dosage of Exparel for local pain management is 266 mg as a one-time single dose.
is that the maximum tolerated dose (MTD) of EXPAREL is higher than the MTD of plain bupivacaine. Maximum tolerated dose is defined as the highest dose level
The maximum recommended dose in children is 266 mg of Exparel. As a local analgesic, Exparel is injected into certain areas of your body to numb them so that
to a maximum dose of 266 mg (20 mL). See Full Prescribing The recommended dose of EXPAREL for local infiltration in adults is up to a maximum dose of.
EXPAREL is intended for single-dose infiltration only. EXPAREL should be administered with a 25 gauge or larger bore needle. The maximum dosage of EXPAREL
from other bupivacaine products to an EXPAREL dose and vice versa (2.1, 2.5). Do not dilute EXPAREL with water or other hypotonic solutions (2.1). The recommended dose of EXPAREL for: o Local infiltration in adults is up to a maximum dose of 266 mg. See Full Prescribing Information for guidance on dose selection (2.2).
The maximum dose of EXPAREL should not exceed 266 mg. EXPAREL can be administered unexpanded (20 mL) or expanded to increase volume up to a total of 300 mL
That said, keep up the story-telling. I'll be watching for part 2.