by K Murakami 2024 Cited by 54In Japan, the guideline proposes that the use of metronidazole in a triple therapy containing PPI, PPI plus amoxicillin and metronidazole is desirable in
metronidazole to PPI-AC triple therapy (PPI-ACM). This may increase PPI-MC PPI with metronidazole and clarithromycin. PUD peptic ulcer disease. R
Helicobacter pylori triple therapy use PPI PLUS clarithromycin PLUS metronidazole if previous clarithromycin, use PPI PLUS bismuth salt PLUS
therapy with bismuth, metronidazole, and tetracycline plus either a PPI or an H2 receptor antagonist (H2RA) (see Table. 3).4 If a PPI is chosen, the regimen can
PPI, bismuth, metronidazole, and tetracycline If that fails, the second line of therapy is triple therapy with PPI, Clarithromycin, and
Bismuth quadruple therapy (PPI, bismuth, tetracycline, and metronidazole [Flagyl] or tinidazole) or concomitant therapy (nonbismuth quadruple therapy; PPI, clarithromycin, amoxicillin, and
Three prospective studies have reported success rates of 74% with a 10 d PPI-Bismuth-Tetracycline-Metronidazole combination, 84.8% with a 14 d PPI-Bismuth-Clarithromycin-Metronidazole regimen and 85.5% with a 14 d PPI-Bismuth-Levofloxacin-Cefuroxime treatment.
What is recommended as primary therapy for H. pylori? PPI metronidazole levofloxacin. PPI metronidazole clarithromycin. PPI amoxicillin
metronidazole 400mg BD. Alternative second line treatment. If previous exposure to metronidazole and clarithromycin. PPI twice daily. PLUS
Comments
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'Brakes' not 'Breaks'.