Valacyclovir is an antiviral drug that belongs to the purine (guanine) nucleoside analog drug class.¹. As a prodrug to acyclovir (Zovirax)
Acyclovir is a Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor, and Herpes Zoster Virus Nucleoside Analog DNA Polymerase Inhibitor, and
Nucleoside analogs potently inhibit these enzymes, positioning them as promising COVID-19 therapeutics. The following section will elaborate on the mechanisms of action employed by these nucleoside analog drugs in targeting the RdRp and methyltransferase activities of SARS-CoV-2.
Nucleoside analogs are valuable commodities in the development of antisense oligonucleotides or as stand-alone antiviral and anticancer therapies. Syntheses of nucleoside analogs are typically
MECHANISMS OF DRUG RESISTANCEAcyclovir, famciclovir, and valacyclovir are antiviral agents within the nucleoside analog class. After
Nucleoside/nucleotide reverse transcriptase inhibitors, also called nucleoside analogs, such as abacavir, emtricitabine, and tenofovir. These medicines are
Nucleoside analogs play a crucial role in the production of high-value antitumor and antimicrobial drugs. Currently, nucleoside analogs are mainly obtained through nucleic acid degradation, chemical synthesis, and biotransformation.
Name: Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor ; Drug, Drug Description ; Drug, Target, Type
Drug Classes:Guanosine Nucleoside Analog, Viral DNA Polymerase Inhibitor, Anti-Infective Agent, Antiviral, Purine Nucleoside Analog. View all. Routes:oral.
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