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Medications like Tylenol and Aleve are hepatotoxic, meaning they could raise liver enzymes and damage your liver over time Ibuprofen Bad for Your Liver and
Most of the other differences between the specific drugs are things like side effects and other interactions (e.g. Aspirin is bad for your stomach, Ibuprofen and Naproxen are bad for your heart, Acetaminophen is bad for your liver).
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