Fluoxetine is predicted to increase the exposure to Amitriptyline. Manufacturer advises monitor for toxicity and adjust dose.
Amitriptyline toxicity is measurable by a dose of over 5 mg/kg. The clinical symptoms of amitriptyline toxicity include neurological, cardiac, and anticholinergic adverse reactions. Neurological symptoms include sedation, seizure, and coma.
by Ş ASLAN 2024 Cited by 23to high dose amitriptyline ingested. Somnolence. (92.5%) was the changes after ingestion of amitriptyline at toxic doses may provide
We describe a case of near fatal amitriptyline overdose in [1] In children doses of 5 mg/kg are po- tentially toxic and severe toxicity is likely at doses of
Amitriptyline toxicity is measurable by a dose of over 5 mg/kg. The clinical symptoms of amitriptyline toxicity include neurological, cardiac, and anticholinergic adverse reactions. Neurological symptoms include sedation, seizure, and coma.
The potentially toxic dose of amitriptyline is 15mg/kg. Toxicity of these highly protein-bound drugs is due to blockade of cardiac sodium
If there is no response to the initial dose, it may be repeated after five minutes. Mechanism of reversal of toxic effects of amitriptyline on
Apo-Amitriptyline(amitriptyline): The treatment of depression including hypertension, palpitaion, arrhythmias, heart block and with toxic doses
Fluoxetine is predicted to increase the exposure to Amitriptyline. Manufacturer advises monitor for toxicity and adjust dose.
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