Is gabapentin an anti inflammatory

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Actual: Is gabapentin an anti-inflammatory? The effect of gabapentin on pain as recently linked to the anti-inflammatory action of the drug. It has been demonstrated (Lee et al, 2024) that gabapentin is able to reduce pro-inflammatory mediators (e.g, TNF-, IL-1, and IL-6) and up-regulates anti-inflammatory cytokine IL-10 in a rat model of neuropathic pain.
4.3 rating 2025-04-24
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Rheumatoid arthritis Multiple sclerosis Chronic pain syndromes Limitations of Gabapentin as an Anti-Inflammatory While Gabapentin shows promise as an anti-inflammatory agent, it is important to note that it may not be as effective as traditional anti-inflammatory drugs in certain cases.

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No: Neurontin (gabapentin) is not an anti-inflammatory, but it can help with nerve pain disorders.

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