QT Prolongation: QT prolongation and ventricular arrhythmia including Fluoxetine can also prolong the QT interval. Clinical studies of pimozide
Concomitant use in patients taking pimozide is contraindicated. Pimozide can prolong the QT interval. Fluoxetine can increase the level of pimozide through inhibition of CYP2D6. Fluoxetine can also prolong the QT interval. Clinical studies of pimozide with other antidepressants demonstrate an increase in drug interaction or QT prolongation.
may cause QT interval prolongation; however QTc Prolongation Associated with Combination Therapy of Levofloxacin, Imipramine, and Fluoxetine.
Anxiety and Insomnia: May occur ; QT Prolongation: QT prolongation and ventricular arrhythmia including Torsades de Pointes have been reported with fluoxetine use. Use with caution in conditions that predispose to arrhythmias or increased fluoxetine exposure. Use cautiously in patients with risk factors for QT prolongation (4.2, 5.11)
QT prolongation: Fluoxetine can prolong the QT interval, possibly leading to torsade de pointes. The drug should be used cautiously in patients with an increased risk of QT prolongation. Cognitive impairment: Fluoxetine can potentially impair cognitive function and motor skills. Per manufacturer labeling, caution should be exercised when
Do not use fluoxetine with pimozide due to risk of QT interval prolongation and drug interaction. Do not use fluoxetine with thioridazine due to risk of QT
MHRA: Safety advice regarding maximum doses and QT prolongation. Fluoxetine fluoxetine tablet) should be prescribed in preference to fluoxetine liquid as
Fluoxetine prolongs the QT interval; the prescribing information for fluoxetine recommends avoiding concurrent use of other drugs that may prolong the QT interval; risk may be increased with higher doses and/or when associated with hypokalemia; drugs that prolong the QTc interval may potentiate the effects of betanists on the
risk of QT prolongation. Avoid, especially in patients at high risk of QT duloxetine, fluoxetine, imipramine, paroxetine). △. △ △. △. CYP1A2
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