Acyclovir and ebv

☑️@acyclovir_and_ebv · 7582 subscribers · Content 18+ 🔞
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Actual: EBV replicates during lytic infection by mechanisms common to all herpesviruses, and EBV lytic infection is inhibited by nucleoside analogues such as acyclovir
4.5 rating 2025-04-27
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Antiviral therapy. Acyclovir is most active in vitro against HSV, with activity against VZV being about tenfold less. Although EBV has only minimal thymidine kinase activity, EBV DNA polymerase is susceptible to inhibition by acyclovir triphosphate and thus EBV is moderately susceptible to acyclovir in vitro.

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The role of antiviral therapies in the treatment of acute and chronic EBV-associated disease is unclear. Acyclovir reduces EBV replication by inhibiting viral DNA polymerase, and studies have found that both acyclovir and the prodrug valacyclovir reduce oral shedding of EBV in patients with infectious mononucleosis.

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by JC Luxton 2024 Cited by 22to receive acyclovir, EBV was not isolated from multi- ple throat washing dose oral acyclovir suppresses EBV replication in the oropharynx of most

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Acyclovir and ganciclovir may reduce EBV shedding, but are ineffective clinically. Treatment of immunocompromised patients with EBV

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Acyclovir and ganciclovir may reduce EBV shedding, but are ineffective clinically. Treatment of immunocompromised patients with EBV

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Acyclovir is an antiviral medication that inhibits DNA polymerase of EBV. Acyclovir s effects on IM have been studied in double-blind, placebo-controlled trials and have demonstrated a suppression in the shedding of EBV in the saliva of infected patients, but EBV replication resumed after treatment was discontinued. 12,13 The use of acyclovir

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Antiviral therapy. Acyclovir is most active in vitro against HSV, with activity against VZV being about tenfold less. Although EBV has only minimal thymidine kinase activity, EBV DNA polymerase is susceptible to inhibition by acyclovir triphosphate and thus EBV is moderately susceptible to acyclovir in vitro.

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by AM Lerner 2024 Cited by 14With valacyclovir, serum EBV titers (EBV, early antigen (diffuse); EBV acyclovir for the treatment of acute infectious mononucleosis. J Infect. Dis

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The Epstein Barr virus (EBV)-encoded protein kinase, EBV-PK, but not the thymidine kinase (EBV-TK), is required for ganciclovir and acyclovir inhibition of lytic viral production. J. Virol.

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