should be used in pregnant women only if the need for strong opioid analgesia morphine IM for every 6 mg of morphine as MS CONTIN. The IM 24-hour dose
by RB Koh 2024 Cited by 57Vomiting may occur after IV, IM, or epidural administration of morphine. The emetic effects of morphine usually occur within 5 minutes after IM
It is estimated that 1.3 mg of intramuscular (IM) hydromorphone is equianalgesic to 10 mg of IM morphine. The relative potency, (based on a single dose bioassay) of oral hydromorphone was found to be approximately one-fifth that of IM hydromorphone, this ratio being similar to that for morphine.
IN ketamine vs. IV morphine vs. IM morphine in acute traumatic pain: 34 IN ketamine, 26 IV morphine, 30 IM morphine: Pain at 5 min interval from 0 to 60 min: IN ketamine may provide analgesia clinically equal to IV or IM morphine: Ketamine group reported increased incidence of difficulty in concentrating, dizziness, confusion: Blancher et al. 2024
Morphine Sulfate. Cardiac Medications / Hemodynamic Medications Intramuscular (IM): (not appropriate for cardiac intervention) 5 – 20 mg IM
IN ketamine vs. IV morphine vs. IM morphine in acute traumatic pain: 34 IN ketamine, 26 IV morphine, 30 IM morphine: Pain at 5 min interval from 0 to 60 min: IN ketamine may provide analgesia clinically equal to IV or IM morphine: Ketamine group reported increased incidence of difficulty in concentrating, dizziness, confusion: Blancher et al. 2024
Morphine up to 15mg IM (given with IM cyclizine or IM prochlorperazine - see monographs). Consider a reduced dose in women ≤ 50kg. A further 2 doses morphine
It is estimated that 1.3 mg of intramuscular (IM) hydromorphone is equianalgesic to 10 mg of IM morphine. The relative potency, (based on a single dose bioassay) of oral hydromorphone was found to be approximately one-fifth that of IM hydromorphone, this ratio being similar to that for morphine.
The volume of distribution (Vd) for morphine is approximately 4 liters per kilogram. morphine IM for every 6 mg of morphine as MS CONTIN. The IM 24
Regards, Jack