Metronidazole should be used in combination with doxycycline to provide extended coverage against anaerobic bacteria.[23]. Outpatient treatment with
Anaerobes: Similar anaerobic coverage as compared to penicillin-G. (5) Gram negative coverage: Doxycycline has reasonably good coverage for E.
While the 2024 CDC guideline for PID does not definitively support anaerobic coverage, the addition of metronidazole to the outpatient ceftriaxone/doxycycline
anaerobic coverage (clindamycin or metronidazole) if required (Table 5). A carbapenem, moxifloxacin, or doxycycline is also appropriate. If
Adding metronidazole for anaerobic coverage to antibiotics already with anaerobic A Randomized Controlled trial of Ceftriaxone and Doxycycline, with or
If concern for MRSA, use vancomycin instead of clindamycin and add anaerobic coverage with NOT adding Amoxicillin or Cephalexin to TMP/SMX, Doxycycline, or
For aspiration pneumonia, Amoxicillin-clavulanate (or other. BLBLIs) is recommended for anaerobic coverage. §Doxycycline is recommended for the treatment of
doxycycline, minocycline, tigecycline) and TMP/SMX. Useful for skin and skin structure infections when some Gram (-) and anaerobic coverage is
anaerobic coverage (clindamycin or metronidazole) if required (Table 5). A carbapenem, moxifloxacin, or doxycycline is also appropriate. If
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