The optimal time to measure QTc is when the QTc-prolonging medication is at steady state. Promethazine (Phenergan). Trazodone (Desyrel). Clozapine (Clozaril).
promethazine. buprenorphine and promethazine both decrease QTc interval. Avoid or Use Alternate Drug. propafenone.
by AJ Schwinghammer 2024 Cited by 12familial long-QT syndrome, and drug-drug interactions that independently prolong the QTc promethazine, and risperidone. Concomitant medication
by N Niimi 2024 Cited by 19Abbreviations: LQTS, Long QT Syndrome; QTc, corrected QT interval. Promethazine significantly lengthens QTc, but has no effect on TDR.
The risk or severity of QTc prolongation can be increased when Trazodone is combined with Promethazine. Propafenone, The risk or severity of QTc prolongation
by B Gray 2024 Cited by 10(6) promethazine and trimipramine both increase QTc interval. Page 58. Pharmacodynamic synergy. (7) promethazine and fluoxetine both increase QTc interval.
buprenorphine, long-acting injection and promethazine both decrease QTc interval. Avoid or Use Alternate Drug. buprenorphine, long-acting injection and promethazine both increase sedation. Avoid or Use Alternate Drug.
The safest antiemeitcs from a QTc prolongation perspective are metoclopramide, prochlorperazine, and promethazine. Trimethobenzamide is also an
Acquired long QT syndrome (aLQTS) is associated with prolongation of the QT interval Promethazine and trimipramine both increase QTc interval.
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