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The pharmacokinetic parameters of riluzole after multiple dose administration (4.5 days of treatment at 50 mg riluzole b.i.d.) are not affected in the elderly ( 70 years). Gender: No gender effect on riluzole pharmacokinetics has been found in young or elderly healthy subjects.

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PART III: CONSUMER INFORMATION. MYLAN-RILUZOLE. (Riluzole Tablets, USP). 50 mg. This leaflet is part III of a three-part Product Monograph published when

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Primary: pooled hazard ratio of tracheostomy‐free survival over all time points with riluzole 100 mg. Secondary: per cent mortality with riluzole 50 mg, 100 mg and 200 mg; neurologic function, muscle strength and adverse events.

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