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Can you take Mucinex and Mucinex DM together? Answer. No, Mucinex and Mucinex DM should not be taken together. Both Mucinex and Mucinex DM contain the active ingredient guaifenesin. While guaifenesin is the only active ingredient in the Mucinex, Mucinex DM contains both guaifenesin and dextromethorphan.
Mucinex DM contains dextromethorphan, a cough suppressant, as an added ingredient. Both ingredients (guaifenesin dextromethorphan) work together to suppress cough. Mucinex DM is a good choice for post nasal drip and in situations where you have excessive coughing and throat irritation. To reiterate, you should not take Mucinex and Mucinex DM
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