In molecular biology and physiology, something is GABAergic or GABAnergic if it pertains to or affects the neurotransmitter gamma-aminobutyric acid (GABA). For example, a synapse is GABAergic if it uses GABA as its neurotransmitter, and a GABAergic neuron produces GABA.
A GABAergic or GABAnergic agent is any chemical that modifies the effects of GABA in the body or brain. Some different classes of GABAergic drugs include agonists, antagonists, modulators, reuptake inhibitors and enzymes.
According to wikipedia Gabapentin is not directly gabaergic, but it's gabaergic properties come from indirect modulation/increased
, nonbenzodiazepine hypnotics (Z-drugs). barbiturates., and melatonin agonists. Most sedative-hypnotic drugs affect. GABAergic. transmission
I want to make it clear that this is a table for GABAergic nootropics, not GABAergic drugs or pharmaceuticals (like strong benzodiazepines which act as potent PAMs and cause fast tolerance build-up). Many GABAergics can impair cognitive functions thus it is imperative that the compounds suggested are also nootropics.
In this review, we are going to summarize the recent findings of both current GABAergic drugs and novel GABAergic drugs and do comparison and evaluation from the evidence we found. Unlike current
Indeed, deficits in GABAergic functions most commonly result in a hyperexcitable epileptic state, and many of the currently used antiepileptic drugs act through enhancement of GABAergic functions. However, a number of observations show that some epileptiform activity patterns involve synchronization by GABAergic mechanisms.
A GABAergic or GABAnergic agent is any chemical that modifies the effects of GABA in the body or brain. Some different classes of GABAergic drugs include agonists, antagonists, modulators, reuptake inhibitors and enzymes. [1]
, nonbenzodiazepine hypnotics (Z-drugs). barbiturates., and melatonin agonists. Most sedative-hypnotic drugs affect. GABAergic. transmission
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