Drugs to increase platelets

Dexamethasone (Decadron) is designed to increase the platelet count by slowing the destruction of platelets.

There are three major causes of insufficient platelets in thrombocytopenia. These include low platelet production in the bone marrow, increased platelet

Anticoagulant drugs can be classified into anti-platelet drugs and anticoagulant agents. Anti-platelet drugs, or platelet aggregation inhibitors, inhibit platelet adhesion, aggregation and secretion through acting on ADP receptors, inhibiting the four arachidonic acid (AA) metabolism and increasing platelet cyclic adenosine monophosphate (cAMP

As in non-immune drug-induced thrombocytopenia, the drug-dependent antibodies and drugs cause thrombocytopenia by cellular processes that (1) increase platelet clearance and/or (2) suppress platelet production. Before these processes can occur, the drug-dependent antibodies and the inducing drugs will have to bind to platelets and/or

How do antiplatelet drugs work? A. Increasing the elimination of formed platelets B. Decreasing the formation of new platelets C. Preventing platelets from aggregating D. Trapping platelets in the spleen

A low platelet count increases the risk of bleeding, especially from the These medicines may contain aspirin or other drugs that can weaken the platelets and

Decreased platelet production Increased splenic sequestration of platelets with normal platelet survival Increased platelet destruction or consumption (both

corticosteroids or a more rapid platelet increase is necessary. platelets are consistently effective in increasing the fetal platelet

platelet production in the bone marrow or increased platelet turnover in the ), drugs (e.g. heparin. ), and other conditions (e.g.