Sildenafil, a PDE5 inhibitor, inhibits the activity of PDE5 enzymes. These enzymes break down cyclic guanosine monophosphate (cGMP), relaxing the penile blood vessels. Sildenafil
Cialis is a brand name for the generic drug tadalafil, a phosphodiesterase 5 (PDE5) inhibitor. PDE5 inhibitors block the PDE5 enzyme to
Viagra and Cialis are in a class of medications called phosphodiesterase type 5 (PDE5) inhibitors. These drugs work by blocking the PDE5 enzyme. These drugs work by blocking the PDE5 enzyme.
Viagra and Cialis are in a class of medications called phosphodiesterase type 5 (PDE5) inhibitors. These drugs work by blocking the PDE5 enzyme. These drugs work by blocking the PDE5 enzyme.
PDE5 is an enzyme that can cause blood vessels to become constricted and narrow. Tadalafil limits the action of the PDE5 enzyme, and so allows for blood to flow into the penis in
Viagra works as a competitive inhibitor to the PDE5 enzymes. In other words, Viagra inhibits the PDE5 enzyme while the sexual stimulation signalling cascade occurs . With
Viagra and Cialis are in a class of medications called phosphodiesterase type 5 (PDE5) inhibitors. These drugs work by blocking the PDE5 enzyme. These drugs work by blocking the PDE5 enzyme.
PDE5 inhibitors block the PDE5 enzyme, which controls blood flow in the corpus cavernosum (the erectile tissue in the shaft of the penis). Blood vessels in the penis are able to relax when the PDE5 enzyme is blocked
Cialis is a brand name for the generic drug tadalafil, a phosphodiesterase 5 (PDE5) inhibitor. PDE5 inhibitors block the PDE5 enzyme to
Comments
To solve the fertility problem, research would produce an enzyme supplement.
Next nit picks - why weren't Sam and Just-in arrested for conspiracy to circulate CP and pervert the course of justice? Why was Sharon not had up for the 2 previous cases and had that added to her sentence?
All in all much better than the direction the car was crashing before you got hold of the wheel.
One nitpick: Telomeres. Umm... I don't think that word means what you think it means. The idea of more telomeres resulting in faster healing is a bit nonsensical. It's sort of like saying to make a car go faster, you should just add more wheels. Yeah, wheels are important... but that's not how you make a car go faster.
Telomeres are simply the end of a DNA strand. Each chromosome is one long piece of DNA. The part at the very ends of that piece are called telomeres. As someone ages, those ends can degrade down and cause problems (or so the theory goes -- there is some debate as to whether this causes aging, or is just a side effect.) Even given the theory that preserving the telomere prevents aging, you don't add more telomeres. You just need to make sure that the existing ones are kept in tact/well repaired.
More telomeres would imply more chromosomes. Ever see someone with Down's Syndrome? It's a sad, horrible condition. That's caused by an extra chromosome.
Easy fix: Say that instead of having more telomeres, he as a higher concentration of telomerase ( note that it ends in 'ase', that means it's an enzyme) Telomerase is an enzyme, the biological machinery that repairs telomeres.
Still not perfect though -- even if you had super-effective telomerase and telomere degredation is largely responsible for aging, that would just prevent aging. It wouldn't necessarily give you super-healing/recharging abilities. Healing/recharging -- that would be more likely due to metabolism and immune system improvements.
Anyway... that was sort of a nitpick that's been grating on my nerves, given that I know something about biology. Overall incredibly creative story, and the rate at which you write is truly impressive. I look forward to more!
The general tone of disapproval from the public and particularly the powers -that-be (the legislators and the courts) and the medical profession has become worse as the technology improved, particularly in the last 10 or so years. There was a small interval mainly in the sixties and early seventies when society loosened up and then another tiny one in the late nineties when the medical profession realized they could make money out of the oldies' sexual dysfunction but here more than any other aspect of health and the body it's now necessary to be forceful and knowedgeable. Don't depend on the MD's to turn you into a super stud or even an old version of such. Do your homework.
You say As for the little blue pills, I never went to the doctor so I've never tried them. I feel my problem was more libido than physical but of course, I could be wrong. Grrrr... Libido is governed by your levels of testosterone which typically drop as we age. Most males of our age should be doing HRT like the women only our H is testosterone. But society hates this idea. Dreams of hormonally charged males raping their virgin grandaughters or synthetically enhanced athletes gaining an unfair advantage underly the discussion. Risks are vastly over-exaggerated probably to assuage the conciences of the blue-noses. The MD's for their part last heard of hormones in medical school years ago but know enough to understand that this is a vastly complex subject and since they see it as recreation (it's no longer procreation at our age) they feel they can fob off the customer with a PDE5 supressor and that's it. Since they won't do it, you have to: homework, homework, homework.
(Some minor insight on T (no substitute for your homework): There are multiple versions of T, some rarely tested for. The amount of T you need depends on the quantity of androgenergic receptors on your cells and their sensitivity. I've never heard of a test for this -- probably only research at the moment. Thus you can have high T levels with low receptor sensitivity and low libido or (as is the case with most teenagers) low T levels and high sensitivity and hence high libido. Teens also have much more of pulsitile production of T (and the other hormones) which appears to raise libido and the sperm production significantly. With old males T level production is almost flat. For current research try the Journal of Andrology and/or the British Journal of Urology (the US one costs money). Again, don't depend on your MD to do YOUR homework.]
IMO every aged male should be on T replacement, take a PDE5 supressor regularly and use some drug to raise the dopamine and/or norepinephrine levels (I use Yohimbine (USP grade) but L-Dopa or apomorphine could substitute - watch for nasty side-effects with these).
It's your body: you don't stop reading because you eyesight has deteriorated do you?
Second, I have been in the medical field approaching 40 years now. While it is true viagra does not directly give you an erection, it does block the enzyme inhibiting, and keeping, one. If he had even the slightest idea of rubbing one out in the shower, viagra would enhance that. And once erect, he would almost certainly keep it, even if running into the other room. Why else do you think they have those legal disclaimers saying to seek medical help if an erection lasts more than four hours?
Third, and last, you do realize this is fiction, right? As long as it's not ridiculous, and there is the ridiculous on here, such as his 15 inch cock pounded her cervix for an hour, then he flipped her over and drilled her ass for another hour, as she continuously came for about 40 times, then I'm good with it. Fiction.
In light of these facts, perhaps it's not the story that is dumb.
TimTam