Using pediatric modified RIFLE criteria, risk, injury, failure, loss of kidney function, and end-stage kidney disease (pRIFLE) for acute kidney injury (AKI), and univariate and multivariate analysis, the investigators establish demographic and clinical factors associated with presumed acyclovir-induced AKI in comparison with a matched cohort of children treated with acyclovir who did not
Acyclovir treatment can cause acute kidney injury because of acyclovir crystal formation in the renal tubules. Yal inkaya R. et al studied risk factors for acyclovir-induced acute kidney injury in children. The retrospective study had a total of 472 patients. Thirty-two had acute kidney injury most patients presented with no symptoms.
It has been previously reported that the nephrotoxicity of acyclovir often causes acute kidney injury (AKI) [ 2, 3 ]. Also, both acyclovir and valacyclovir
Acyclovir intravenous infusion is typically linked to the side effects of acute kidney injury. Acyclovir falls under the category of medications known as
As a prodrug of acyclovir, valacyclovir may also cause acute kidney injury (Ref). Like acyclovir, this may result most often from obstructive nephropathy but
Abstract and Figures. Acute kidney injury is an unfortunate complication of acyclovir therapy secondary to crystal-induced nephropathy. It is
Acute kidney injury (similar to acyclovir as a prodrug) Neurotoxicity Transaminase elevations Anemia, neutropenia Hypotension Thrombotic
Other antiviral medications, such as acyclovir (Zovirax) and ganciclovir, can also cause kidney injury. These are used to treat osteoporosis. Kidney damage is
Acute kidney injury (similar to acyclovir as a prodrug) Neurotoxicity Transaminase elevations Anemia, neutropenia Hypotension Thrombotic
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