by T FUKUSHIMA 2024 Cited by 28Recently, prophylactic effects of low-dose acyclovir (400 mg daily) ( ), and ultra-low-dose acyclovir (200 mg daily) were reported (16). While acyclovir
Although the minimal effective dose of acyclovir for prophylaxis has not yet established, the efficacy of low-dose acyclovir prophylaxis, 400 mg once daily, has been suggested. Methods: We retrospectively reviewed the patients receiving the low-dose acyclovir which was defined as the once daily administration of acyclovir 400 or 200 mg.
Valacyclovir, at a dose of 250 mg four times daily, generates essentially the same acyclovir AUC (area under the curve, or exposure over 24 hours) as oral acyclovir at a dose 800 mg five times daily . Valacyclovir, at a dose of 1000 mg three times daily, produces a similar acyclovir AUC as intravenous acyclovir at a dose of 5 mg/kg every eight
Valacyclovir, at a dose of 250 mg four times daily, generates essentially the same acyclovir AUC (area under the curve, or exposure over 24 hours) as oral acyclovir at a dose 800 mg five times daily . Valacyclovir, at a dose of 1000 mg three times daily, produces a similar acyclovir AUC as intravenous acyclovir at a dose of 5 mg/kg every eight
Acyclovir was dosed five times daily, and valacyclovir was dosed only twice daily. It found no clinically significant difference in the lesion
Valacyclovir, at a dose of 250 mg four times daily, generates essentially the same acyclovir AUC (area under the curve, or exposure over 24 hours) as oral acyclovir at a dose 800 mg five times daily . Valacyclovir, at a dose of 1000 mg three times daily, produces a similar acyclovir AUC as intravenous acyclovir at a dose of 5 mg/kg every eight
The bioavailability of oral acyclovir is relatively low compared to valacyclovir and famciclovir. Acyclovir is typically dosed. 5 times daily
Despite these findings, the serum levels of acyclovir achieved with standard acyclovir dosing (200 mg five times daily or 400 mg three times daily) exceed
Acyclovir was dosed five times daily, and valacyclovir was dosed only twice daily. It found no clinically significant difference in the lesion
Comments