Dose of sugammadex

Options for endotracheal intubation include succinylcholine, intubation without an NMBA (eg, high dose remifentanil intubation, although this technique is associated with more trauma), or rocuronium or vecuronium if sugammadex is available for rapid reversal of block. (See 'Sugammadex' below.)

A dose of 2 mg/kg of sugammadex after continuous rocuronium infusion is enough to reverse the NMB when first response in the Train-Of-Four is reached. Efficacy of different doses of sugammadex after continuous infusion of rocuronium

In this case, no AEs related to sugammadex were observed, despite the high dose of sugammadex. This may contribute to expanding the safety profile of sugammadex and its use in patients with renal failure. In addition, this case suggests that dose modification of sugammadex may be necessary for patients with ESRD.

Options for endotracheal intubation include succinylcholine, intubation without an NMBA (eg, high dose remifentanil intubation, although this technique is associated with more trauma), or rocuronium or vecuronium if sugammadex is available for rapid reversal of block. (See 'Sugammadex' below.)

Purpose. The use of sugammadex at a lower dose after a routine reversal dose of neostigmine may prevent residual neuromuscular blockade (rNMB). Our goal was to investigate the effects of the use of half-dose sugammadex for reversing rNMB after administration of neostigmine, and compare these effects to a routine full-dose of neostigmine.

Third, beyond comparing the cost of vials, we compared the actual cost of reversal (cost of all vials for total dose of sugammadex versus cost of all vials for total doses of neostigmine plus glycopyrrolate) and found sugammadex reversal cost was over 5 times greater for sugammadex ($117 vs $21).

Prior to sugammadex, the rate of residual neuromuscular blockade was %, which means that our pre-sugammadex practices worked for % of

The mass of one molecule (or mole) of sugammadex is 3.6x that of rocuronium. If you've given 0.6mg/kg roc, the dose of sugammadex to give the

The recommended dose of sugammadex depends on the level of neuromuscular blockade to be reversed. The recommended dose does not depend on the anaesthetic regimen. Sugammadex can be used to reverse different levels of rocuronium or vecuronium induced neuromuscular blockade: Adults Routine reversal: