Pristiq and Effexor are basically the same drug, although Pristiq is a concentrated version of Effexor, in other words Pristiq is stronger, and both drugs are difficult to withdrawal from. I think because you switched out 50mg of Pristiq for 37.5mg of Effexor is the reason you are having such difficultly (as well as the 50% reduction of Pristiq).
The main difference between Pristiq (desvenlafaxine) and Effexor (venlafaxine) is that Pristiq is the active form of Effexor. Effexor contains
Now comes Pristiq (desvenlafaxine), spawn of Effexor (you guessed it, venlafaxine). This one's also a simple metabolic change, OH from O-methyl.
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Switching From Pristiq To Effexor. A doctor may recommend switching Pristiq vs Lexapro. Lexapro is an antidepressant that treats the
Other SNRIs are duloxetine (Cymbalta) or desvenlafaxine (Pristiq). Effexor And Weight Changes Effexor Vs. Other Drugs. 24/7 Treatment
Pristiq for sure. But I ended up changing to Effexor XR (it's metabolized partially into pristiq) high dose in the end. The pristiq was very tolerable but I didn't benefit from it that much. Effexor has been less energetic for sure but do far has worked better for me.
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