Absorption. Oral prednisone has a T max of 2 hours, while the delayed-release formulation has a T max of 6-6.5 hours. 9 A 5mg dose of prednisone has an AUC of 572mL/min/1.73m 2, a 20mg dose of prednisone has an AUC of 1034mL/min/1.73m 2, and a 50mg dose of prednisone has an AUC of 2271mL/min/1.73m 2. 5 Data regarding the C max of prednisone is not readily available. 9
Absorption. Oral prednisone has a T max of 2 hours, while the delayed-release formulation has a T max of 6-6.5 hours. 9 A 5mg dose of prednisone has an AUC of 572mL/min/1.73m 2, a 20mg dose of prednisone has an AUC of 1034mL/min/1.73m 2, and a 50mg dose of prednisone has an AUC of 2271mL/min/1.73m 2. 5 Data regarding the C max of prednisone is not readily available. 9
Max dose 25 mg. Dosing: ANAPHYLAXIS ALLERGIC REACTION. Indication Prednisone PO is preferred over methylprednisolone for respiratory distress however.
High supra-physiologic: mg (max adrenal output). Dosing Instructions Consider PCP prophylaxis if using equivalent steroid dose to prednisone 20mg daily
Prednisone/Prednisolone 1mg/kg orally – max 60mg/dose – once daily for 5 days (Fun-fact: Prednisone is metabolized into prednisolone in the liver)
Absorption. Oral prednisone has a T max of 2 hours, while the delayed-release formulation has a T max of 6-6.5 hours. 9 A 5mg dose of prednisone has an AUC of 572mL/min/1.73m 2, a 20mg dose of prednisone has an AUC of 1034mL/min/1.73m 2, and a 50mg dose of prednisone has an AUC of 2271mL/min/1.73m 2. 5 Data regarding the C max of prednisone is not readily available. 9
Prednisone/Prednisolone 1mg/kg orally – max 60mg/dose – once daily for 5 days (Fun-fact: Prednisone is metabolized into prednisolone in the liver)
What is the usual dose schedule for oral medications? There are a few options: Prednisone/Prednisolone 1mg/kg orally – max 60mg/dose – once daily for 5
Methylprednisolone (Solu-medrol). mg/kg/dose IV (max Hydrocortisone potency is NOT equivalent to that of prednisone/prednisolone.
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