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Author: Admin | 2025-04-28
Randomized, controlled trials supports the use of clonazepam in the treatment of acute bipolar mania Curtin 2004. Additional trials may be necessary to further define the role of clonazepam in this condition.APA guidelines for the treatment of patients with bipolar disorder suggest that the use of benzodiazepines, such as clonazepam, in sedative doses may be useful short-term as adjunctive therapy when used with traditional mood-stabilizing agents. CANMAT guidelines for the management of patients with bipolar disorder recommend against the use of benzodiazepines as monotherapy, but suggest they may be useful adjunctive therapy for the sedation of acutely agitated patients. Similarly, WFSBP guidelines for the treatment of acute mania in bipolar disorder recommend benzodiazepines as adjunctive therapy to target anxiety and insomnia in patients taking mood-stabilizing agents.Burning mouth syndromecData from a prospective open-label study in patients with mouth burning without oral mucosal lesions suggest that clonazepam may be helpful in patients with this condition Grushka 1998. Additional data from a double-blind, randomized, multicenter, parallel group study using topical (buccal administration) clonazepam demonstrated improvement in pain intensity Gremeau-Richard 2004. In a systematic review, clonazepam is a therapeutic option in the treatment of this condition; however, use should be limited due to the risk of benzodiazepine dependence Buchanan 2008. Additional trials are necessary to further define the role of clonazepam for the treatment of this condition.Essential tremorcyesData from a limited number of patients studied (case series) suggest that clonazepam may be beneficial in reducing the frequency of essential tremor Biary 1987. On the contrary, data from a small randomized, double-blind, placebo-controlled trial demonstrated that clonazepam was not an effective treatment Thompson 1984. Additional data may be necessary to further define the role of clonazepam in this condition.Based on the American Academy of Neurology guidelines for the treatment of essential tremor, clonazepam is possibly
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