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Author: Admin | 2025-04-28
Of medications that act in a similar way.) COX-2 inhibitors are a type of NSAID. So after Vioxx and Bextra were withdrawn from the market, a large clinical trial was carried out to check the safety of Celebrex.Researchers found that the risks of heart attack and stroke with Celebrex were much lower than with Vioxx or Bextra. The trial also found that the risks were lower with Celebrex than with high doses of naproxen or ibuprofen. (Naproxen and ibuprofen are widely used and commonly prescribed NSAIDs, but they aren’t COX-2 inhibitors.)Based on the results of this clinical trial, the FDA decided that the benefits of Celebrex outweigh its risks.Celebrex is a type of pain reliever called a nonsteroidal anti-inflammatory drug (NSAID). It reduces inflammation and relieves pain for various conditions. Celebrex is used to treat certain forms of arthritis as well as acute pain, including menstrual cramps. (“Acute” means short term.) For details on the conditions the drug treats, see the “Celebrex uses” section above.What causes the pain?If you have damage to tissues in your body, such as following an injury or surgery, or due to arthritis, your body makes prostaglandins. These are hormones created by an enzyme called cyclooxygenase (COX). Prostaglandins are made as part of the healing process, but they also cause inflammation and pain.Prostaglandins are also responsible for causing the uterus to contract during menstrual periods. The contractions cause the lining of the uterus to be expelled, and they also cause menstrual cramps.What does Celebrex do?Celebrex works by stopping COX from making prostaglandins. This reduces inflammation and relieves pain.How long does it take to work?Celebrex starts to work soon after you start taking it. The drug can typically relieve acute pain such as menstrual cramps or pain following surgery within 60 minutes of taking a dose.The anti-inflammatory effect of Celebrex takes a little longer. If you have arthritis, you may need to take Celebrex for a few days before it reaches its full effect. However, in clinical trials, Celebrex was found to significantly reduce osteoarthritis pain within 24–48 hours of starting treatment.How long does Celebrex stay in
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