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Author: Admin | 2025-04-28
All lifestyle recommendations given to you by your doctor (such as losing weight if overweight, smoking cessation, partaking in regular exercise, and limiting sodium intake) should also be followed. In addition, other conditions, such as high cholesterol levels or diabetes if present, also need to be controlled.Do not take any other medications including those bought over-the-counter without checking with your doctor or pharmacist that they are compatible with Entresto. 6. Response and effectiveness Comparative trials have shown that Entresto was superior to enalapril in reducing the risk of cardiovascular death or hospitalization for heart failure. Entresto also improved overall survival. These results were consistent across all subgroups analyzed.In children aged one to less than 18 years, Entresto reduced baseline NT-proBNP by 44% compared to 33% with enalapril, indicating improved cardiovascular outcomes in pediatric patients. 7. Interactions Medicines that interact with Entresto may either decrease its effect, affect how long it works, increase side effects, or have less of an effect when taken with Entresto. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be managed. Common medications that may interact with Entresto include:antipsychotics, such as aripiprazole, clozapine, or haloperidolaspirinbupropionbuprenorphinecorticosteroids, such as budesonide, betamethasone, or prednisonecyclosporineheart medications, including all ACE inhibitors or ARBs, such as benazepril, captopril, fosinopril, or lisinoprilinsulinNSAIDs, such as diclofenac, ibuprofen, or indomethacin other heart medications, such as amiodarone, clonidine, digoxin, diltiazem, propafenone, quinidine, and verapamilother medications including celecoxib, clonidine, hydralazine, and rifampicinpotassium saltspotassium-sparing diuretics such as spironolactone, triamterene, or amiloridesildenafiltrimethoprimzolpidem.People taking oral medications for diabetes may need to talk to their doctor about adjusting the dose of their medicine. Note that this list is not all-inclusive and includes only common medications that may interact with Entresto. You should refer to the prescribing information for Entresto for a complete list of interactions. References Entresto (sacubitril and valsartan) [Package Insert] Updated 02/2024. Novartis Pharmaceuticals Corporation. https://www.drugs.com/pro/entresto.html Further informationRemember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Entresto only for the indication prescribed.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Copyright 1996-2025 Drugs.com. Revision date: May 16, 2024.Medical Disclaimer
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