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Author: Admin | 2025-04-28
Correctly, it can reduce the sexual side effects sometimes associated with the other medication.Buspirone is FDA-approved for the treatment of anxiety, and as an FDA-approved medication, it’s fairly effective in treating the condition.A review of literature on Buspirone collected data from over 1,000 outpatients with anxiety. What it found was that a 20mg dose per day was as effective as other medications like diazepam and clorazepate, while managing to cause fewer side effects. Buspirone was less likely to intensify the effects of alcoholic beverages than other medications, did not seem to cause abuse of the medication itself, and impaired motor performance less significantly than other medications.The biggest limitation to this data, however, is that it was compiled in 1984. There hasn’t been significant research into buspirone since then, with a few exceptions. One exception is a review from 2015, which updated current opinions on buspirone. That review found that buspirone is effective for generalized anxiety disorder specifically, but failed to treat other forms of anxiety.They did however note additional benefits to treating irritability and aggression in patients with dementia, and posited that there was promise in a combination of melatonin and buspirone for treatment of depression.How buspirone works is a bit complicated, but in the simplest explanation, it’s in a class of medications called azapirones, which affect serotonin receptors in the brain. From the way the NIH explains it, buspirone seems to thread the needle in the world of neurotransmitters: it weakly affects certain dopamine receptors, avoids the receptors affected by benzodiazepines, and targets the 5HT2 and 5HT1 serotonin receptors, both of which seem to make it effective in managing anxiety. In other words, buspirone tends to affect a lot of things a little bit. Since everyone’s brain chemistry equilibrium is a little different, this medication has significant value —
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