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Author: Admin | 2025-04-28
In pregnancy. I had an allergy reaction to Losec (or another PPI). Can I take a different PPI? No. This often means that you will also react to the other PPIs. If you have any symptoms or signs suggestive of an acute allergic reaction (anaphylaxis), you must get medical help immediately (telephone 999 if in the UK). Symptoms/signs of an acute allergic reaction include: Difficulty breathing, tight chest, wheezing. Swelling of the face, lips, or tongue. Skin rash - urticaria/hives. Confusion/collapse/unconsciousness. I am due a medical investigation or blood test should I stop my PPI? Possibly. PPIs can interfere with the results of some blood tests, or hide serious conditions during endoscopy. Let the doctor or nurse know that you are taking a PPI. You may have to stop it for up to a few weeks, to prevent it interfering with the results. Why can't I buy Zantac (ranitidine) anymore? Zantac/ranitidine was withdrawn by the manufacturers in October 2019, due to the discovery of the contaminant N-nitrosodimethylamine (NDMA) which has genotoxic and carcinogenic potential - further details. It is unclear if and when production will start again (April 2024). Although Zantac is from a different class of drug (H2 receptor antagonists), the PPIs Losec (omeprazole), Nexium (esomeprazole), lansoprazole, or pantoprazole can be taken as an alternative. What is H. pylori? H. pylori stands for Helicobacter Pylori which are bacteria that can live in the stomach and cause inflammation. It is thought up to 40% of the UK population has this
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