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Author: Admin | 2025-04-28
#21 Alright, so the effects of Cialis have really started to dwindle. Yesterday I took 20mg and I really couldn't even feel it. When I used to take 10 my penis would look large and in charge even when it was flaccid and I could get a rock hard erection in a moments notice. Has my body adapted to it? Whats the highest dosage anyone has tried? Any other input? Tadalafil is also used to treat pulmonary hypertension (PAH) under the trade name Adcirca. In this manner the usual starting dose is 40mg daily, and titrated up to 60mg (20 mg TID) depending on the response. You really have to be conscious of the nitrate interaction, or you’ll be found unconscious. Tadalafil - Pulmonary Hypertension Association #23 And as we all know pineapple juice retards the breakdown of PED5 drugs. These chemicals inhibit key drug metabolizingenzymes, such as cytochrome P450 3A4 (CYP3A4). CYP3A4 is a metabolizing enzyme for almost 50% of drugs, and is found in the liver and small intestinal epithelial cells. So pineapple juice greatly increases the prolonged circulating levels of PED5 drugs and also the side effects (priapism) #24 And as we all know pineapple juice retards the breakdown of PED5 drugs. These chemicals inhibit key drug metabolizingenzymes, such as cytochrome P450 3A4 (CYP3A4). CYP3A4 is a metabolizing enzyme for almost 50% of drugs, and is found in the liver and small intestinal epithelial cells. So pineapple juice greatly increases the prolonged circulating levels of PED5 drugs and also the side effects (priapism) Pineapple juice? Interesting. Grapefruit juice enhances the effects of other drugs, I wonder if it has a similar effect on PDE 5? I've tried to increase the effects using NO stimulating supplements but that didn't seem to have any effect. Maybe time to try
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