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Author: Admin | 2025-04-28
Penicillin or amoxicillin are considered the best first-line treatments for Strep throat. According to the CDC (Centers for Disease Control and Prevention) “There has never been a report of a clinical isolate of group A strep that is resistant to penicillin”.For people with a penicillin allergy, treat Strep throat with either a narrow-spectrum cephalosporin (such as cephalexin or cefadroxil), clindamycin, azithromycin, or clarithromycin. Note that resistance to azithromycin and clarithromycin has been reported.What are the recommended dosages of antibiotics used to treat Strep throat?Antibiotic dosages can vary depending on age and weight. The CDC recommends the following dosages of antibiotics for Strep throat, for those people without a penicillin allergy. One dosage regimen should be chosen that is appropriate for the person being treated.Oral Penicillin V Children: 250mg twice daily or 250mg three times daily for 10 daysAdolescents and adults: 250mg four times daily or 500mg twice daily for 10 daysOral amoxicillinChildren and adults: 50 mg/kg once daily (maximum 1000mg once daily) for 10 daysChildren and adults: 25 mg/kg twice daily (maximum 500mg twice daily) for 10 daysIntramuscular Benzathine penicillin G Children Children and adults ≥27 kg: 1 200 000 units as a single doseThe CDC recommends the following dosages of antibiotics for Strep throat, for those people with a penicillin allergy. One dosage regimen should be chosen that is appropriate for the person being treated.Oral cephalexin 20 mg/kg twice daily (maximum 500 mg twice daily) for 10 daysOral cefadroxil 30 mg/kg once daily (maximum 100mg once daily) for 10 daysOral clindamycin 7 mg/kg three times daily (maximum 300 mg three times daily) for 10 daysOral azithromycin 12 mg/kg once daily for the first day (maximum 500 mg), followed by 6 mg/kg once daily (maximum 250 mg once daily) for the next 4 daysOral clarithromycin 7.5 mg/kg twice daily (maximum 250 mg twice daily) for 10 days.Are antibiotics always necessary to treat a Strep throat?Although most Strep throats will get better by themselves, there is a risk of acute rheumatic fever and other complications (such as oral abscesses or mastoiditis [a bacterial infection in the mastoid process, which is the prominent bone behind the ear]) occurring. The CDC recommends that all patients, regardless of age, who have a positive rapid antigen detection test (RADT) (also known as the rapid streptococcal test, which detects the presence of GABHS cell wall carbohydrate from swabbed material) or throat culture receive antibiotics.Antibiotics have been shown to:Shorten the duration of Strep throat symptomsReduce the likelihood of transmission to family members, friends, and other close contactsPrevent the development of rheumatic fever and other complications.Viral sore throats should not be treated with antibiotics. Treatment is usually given for ten days and liquid antibiotics can be given to
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