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Author: Admin | 2025-04-28
Effective for the treatment of this condition.Rapid eye movement (REM) sleep behavior disorderyesBased on the American Academy of Sleep Medicine (AASM) Best Practice Guide for the Treatment of REM Sleep Behavior Disorder (RBD), clonazepam is an effective and recommended treatment option for patients with this condition; however, it should be used with caution in patients with dementia, gait disorders, or concomitant obstructive sleep apnea AASM [Aurora 2010].Restless legs syndromecData from a limited number of patients in small controlled trials suggest that clonazepam may be beneficial for the treatment of periodic limb movements and poor sleep associated with restless legs syndrome Montagna 1984, Peled 1987, Saletu 2001, Schenck 1996. Additional data may be necessary to further define the role of clonazepam in this condition.Based on the updated Tardive dyskinesiacyesData from a limited number of patients in a double-blind, randomized, placebo-controlled crossover trial suggests that clonazepam may be beneficial for the treatment of tardive dyskinesia Thaker 1990. Additional data may be necessary to further define the role of clonazepam in this condition.Based on the American Academy of Neurology guideline for the treatment of tardive syndromes, clonazepam given for tardive dyskinesia is probably effective in decreasing tardive dyskinesia symptoms in the short-term (approximately 3 months) and is suggested for the short-term treatment of tardive dyskinesia.Tic disorderscData from a limited number of patients studied in a single-blind and two retrospective studies suggest that clonazepam may be beneficial for multifocal tic disorder or Tourette disorder. Additional data may be necessary to further define the role of clonazepam in these conditions. ContraindicationsHypersensitivity to clonazepam, other benzodiazepines, or any component of the formulation; significant liver disease; acute narrow-angle glaucomaCanadian labeling: Additional contraindications (not in US labeling): Severe respiratory insufficiency; sleep apnea syndrome; myasthenia gravis Dosage and AdministrationDosing: AdultPanic disorder: Oral: 0.25 mg twice daily; increase in increments
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