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Author: Admin | 2025-04-28
CID 9926791 MedlinePlus a613025 ChEBI 71200 ATC code J05AX25 DrugBank DB13997 KEGG D11021 Routes of administration By mouth (tablets) Cautions Who should avoid taking Xeljanz?Do not take Xeljanz if you have a known allergy to any of the ingredients.Avoid Xeljanz if you are at an increased risk of blood clots.What are the risks?Xeljanz has a black box warning regarding serious infections, malignancy, and thrombosis. Review the full warning in the package insert and discuss your risks with your doctor.You should not receive live vaccinations while using Xeljanz. Discuss alternative vaccine options with your doctor or pharmacist.Xeljanz can increase your risk of skin cancer.Xeljanz can increase your blood lipid levels.Xeljanz can increase your risk of gastrointestinal perforation.Xeljanz can increase your risk of infection.Xeljanz can cause a decrease in your white blood cell count. Your doctor should monitor your blood before you start using Xeljanz and periodically while you are in treatment.Xeljanz can damage your liver. Discuss your risk with your doctor.Tell your doctor if you have a history of tuberculosis.Tell your doctor if you have ever had hepatitis B. infection.If you are being treated for rheumatoid arthritis, you could have an increased risk of pulmonary embolism. Discuss your risk with your physician. Side Effects What are the common side effects of Xeljanz?Increased HDL and LDL levelsHeadacheUrinary tract infectionNasopharyngitisUpper respiratory infectionWhat are the serious side effects?Skin cancerGastrointestinal perforationAnemiaDecreased lymphocyte countDeep vein thrombosisNeutropeniaThrombosisLiver injuryInfectious diseaseLymphoproliferative disorder following transplantationOpportunistic infectionTuberculosisEpstein Barr virusPulmonary embolismOther ConsiderationsCompare the Xeljanz cost at Canada Pharmacy to your local drug store. Frequently Asked Questions about Xeljanz (Tofacitinib) What is Xeljanz (Tofacitinib) used for? Xeljanz is prescribed to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis by inhibiting specific enzymes that contribute to inflammation. How does Xeljanz work? Xeljanz works by targeting and inhibiting Janus kinase enzymes, reducing inflammation and modifying the immune response in conditions like arthritis and ulcerative colitis. What are the common side effects of Xeljanz? Common side effects may include upper respiratory tract infections, headache, and high blood pressure. Consult your doctor for a complete list and guidance. Can Xeljanz be used in combination with other medications? Your healthcare provider may prescribe Xeljanz alone or in combination with other medications based on your specific medical condition. Always follow your doctor's instructions. Is Xeljanz safe during pregnancy and breastfeeding? Consult your healthcare provider before using Xeljanz if you are pregnant, planning to become pregnant, or breastfeeding. Individual circumstances
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