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Author: Admin | 2025-04-28
With venlafaxine therapy. Effexor XR should be prescribedwith caution in patients with a seizure disorder.Hyponatremia: Hyponatremia can occur as a result of treatment with Effexor XR. Considerdiscontinuation of Effexor XR in patients with symptomatic hyponatremia.Interstitial Lung Disease and Eosinophilic Pneumonia: Interstitial lung disease andeosinophilic pneumonia associated with venlafaxine therapy can occur and have been rarelyreported.Sexual Dysfunction: Effexor XR may cause symptoms of sexual dysfunction.The most common adverse reactions (incidence ≥ 5% and at least twice the rate of placebo):nausea, somnolence, dry mouth, sweating, abnormal ejaculation, anorexia, constipation,impotence, and decreased libido.Interference with Cognitive and Motor Performance: Caution patients about operatinghazardous machinery, including automobiles, until they are reasonably certain that Effexor XRtherapy does not adversely affect their ability to engage in such activities.Advise patients to avoid alcohol while taking Effexor XR.Pregnancy: Third trimester use may increase risk for symptoms of poor neonatal adaptation(respiratory distress, temperature instability, feeding difficulty, hypotonia, tremor, irritability) inthe neonate.Hepatic Impairment: Dosage adjustment is recommended in patients with mild, moderate, orsevere hepatic impairment or hepatic cirrhosis.Renal Impairment: Dosage adjustment is recommended in patients with mild, moderate, orsevere renal impairment, and in patients undergoing hemodialysis.IndicationsEffexor XR (venlafaxine extended-release) capsules are indicated in adults for the treatment ofmajor depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder(SAD), or panic disorder (PD).Please see Full Prescribing Information, including BOXED WARNING and Medication Guide.
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