Comment
Author: Admin | 2025-04-28
Published: Dec 26, 2018 Last Updated: Oct 25, 2019 Effexor (venlafaxine) is reported to have adverse effects on the prostate. Dec 26, 2018 William asked Does Effexor XR raise you PSA number? I’m taking 150 mg and it’s new to me. My rise in PSA is also new since being on Effexor. My trips to the bathroom have been more frequent and more urgent. At a glance Effexor is associated with an increased risk of prostatic disorders, such as prostatitis, enlarged prostate, and prostate irritability, all of which can cause an increase in PSA levels. This may be due to its actions on the neurotransmitter norepinephrine. Answer Effexor XR (venlafaxine extended-release) can affect the prostate but is not directly associated with increased PSA (Prostate-Specific Antigen) levels. There is a correlation between elevated PSA levels and prostate cancer. However, cancer is not the only reason that PSA levels may be increased (1). Other reasons your PSA may be elevated include: AgeBPH (benign prostatic hyperplasia)Inflamed prostateConcomitant medicationsVarious medical procedures (e.g. rectal exam) The prescribing information for Effexor lists 'prostatic disorder' as a 'frequent' side effect of the medication. Specifically, it is linked to: ProstatitisEnlarged prostateProstate irritability The above could certainly cause increased PSA levels. However, there is a lack of documented cases in which Effexor has been definitively linked to increased PSA levels specifically. One case study reported on a male complaining of symptoms of prostatism after initiating therapy with Effexor.However, PSA levels in the individual remained normal: References Effexor XR Prescribing Information. AccessFDA Venlafaxine-induced prostatism: a case report. Psychiatry and Clinical Psychopharmacology Evaluating Men with Benign Prostatic Hyperplasia. PubMed Lipitor Prescribing Information. Access FDA Grapefruit Juice and Statins. PubMed Dr. Brian Staiger Pharm.D Dr. Brian Staiger is a licensed pharmacist in New York State and the founder of the Q+A website PharmacistAnswers.com. He graduated from the University At Buffalo with a Doctor of Pharmacy degree in 2010.He has been featured in numerous publications including the Huffington Post as well as a variety of health and pharmacy-related blogs.Please feel free to reach out to him directly if you have any inquiries or want to connect! He's answered thousands of medication and pharmacy-related questions and he's ready to answer yours! Related Questions Ready for a more personal experience with your meds?
Add Comment