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Author: Admin | 2025-04-28
Package insert / product labelGeneric name: maropitant citrateDosage form: FOR ANIMAL USE ONLY CAUTION Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. Cerenia Description Maropitant is a neurokinin (NK1) receptor antagonist that blocks the pharmacological action of substance P in the central nervous system (CNS). Maropitant is the non-proprietary designation for a substituted quinuclidine. The empirical formula is C32H40N2O C6H8O7 H2O and the molecular weight 678.81. The chemical name is (2S,3S)-2-benzhydryl-N-(5-tert-butyl-2-methoxybenzyl) quinuclidin-3-amine citrate monohydrate. Each peach-colored oval tablet is scored and contains 16, 24, 60 or 160 mg of maropitant as maropitant citrate per tablet. The chemical structure of maropitant citrate is: INDICATIONS CERENIA (maropitant citrate) Tablets are indicated for the prevention of acute vomiting and the prevention of vomiting due to motion sickness in dogs. Cerenia Dosage and Administration CERENIA Tablets are recommended for use in dogs 16 weeks and older. For Prevention of Acute Vomiting Administer CERENIA Tablets orally at a minimum dose of 2 mg/kg (0.9 mg/lb) body weight once daily for up to 5 consecutive days. Prevention of Acute Vomiting Minimum of 2 mg/kg BW Dosing Dog body weightNumber of Tablets PoundsKilograms16 mg24 mg60 mg 2.2 – 8.81.0 – 4.0½ 8.9 – 17.64.1 – 8.01 17.7 – 26.48.1 – 12.01 26.5 – 52.812.1 – 24.02 52.9 – 66.024.1 – 30.01 66.1 – 132.030.1 – 60.02 CERENIA Tablets may be used interchangeably with CERENIA Injectable Solution for once daily dosing for the prevention of acute vomiting. For Prevention of Vomiting Due to Motion Sickness Administer CERENIA Tablets orally at a minimum dose of 8 mg/kg (3.6 mg/lb) body weight once daily for up to 2 consecutive days. Dogs should be fasted 1 hour prior to administration of CERENIA Tablets. Administer CERENIA Tablets 2 hours prior to travel. Prevention of Vomiting due to Motion Sickness Minimum of 8 mg/kg BW Dosing Dog body weightNumber of Tablets PoundsKilograms16 mg24 mg60 mg160 mg 2.21½ 2.3 – 3.31.1 – 1.5½ 3.4 – 4.41.6 – 2.01 4.5 – 6.62.1 – 3.01 6.7 – 8.83.1 – 4.02 8.9 – 13.24.1 – 6.02 13.3 –
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