Comment
Author: Admin | 2025-04-28
Therapeutic effect derived from Lexapro – for a subset of users. Once the neuroplastic changes have occurred (e.g. hippocampal neurogenesis), it may seem as though the medication has finally “kicked in” or begun working.Source: https://www.ncbi.nlm.nih.gov/pubmed/28394502Starting Lexapro dosage & titration rateThe specific dose of Lexapro that’s administered at the beginning of treatment and/or how quickly you titrate the dosage upwards might influence the onset of Lexapro’s action. A person initiating treatment a low dose of Lexapro (e.g. 5 mg per day) may undergo significantly less neurophysiologic modulation early in treatment – compared to a person who initiates treatment with a relatively high Lexapro dose (e.g. 20 mg per day).Essentially, a 20 mg dose of Lexapro might exert 2-fold greater serotonin reuptake inhibition than a 10 mg dose. For this reason, someone taking 20 mg of Lexapro to start treatment may notice the medication working quicker than if he/she started with just 10 mg. Additionally, longer-term neurophysiologic adaptations to Lexapro such as 5-HT1A receptor downregulation and hippocampal neurogenesis may occur at a faster rate in high dose users.Persons who begin Lexapro treatment with a lower dose might not notice the medication working right away due to the fact that the dose isn’t high enough to substantially modify neurochemistry and/or facilitate a therapeutic effect. A psychiatrist (or medical doctor) may recommend gradually titrating the dosage upwards (i.e. increasing the dose) for a new user such as by increasing from 10 mg to 20 mg after several weeks of treatment.Following the titration phase or
Add Comment