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Author: Admin | 2025-04-28
Induced adverse bronchopulmonary effect; porphyria. Dosage and AdministrationDosing: AdultAntiemetic: IM: 25 to 100 mg/doseAnxiety:Oral:Manufacturer’s labeling: 50 to 100 mg 4 times dailyAlternative recommendations (off-label dosing): 37.5 to 75 mg daily in divided doses (WFSBP [Bandelow 2008]; WFSBP [Bandelow 2012])IM: Initial: 50 to 100 mg, then every 4 to 6 hours as neededPeripartum adjunct: IM: 25 to 100 mgPerioperative adjunct:Oral: 50 to 100 mgIM: 25 to 100 mgPruritus: Oral: 25 mg 3 to 4 times dailyDosing: GeriatricAvoid use (Beers Criteria [AGS 2019]).Dosing: PediatricAntiemetic: Note: Expert recommendations for postoperative nausea and vomiting (PONV) management do not suggest hydroxyzine as a therapeutic option; use has typically been replaced by newer agents with an improved safety profile (SAA [Gan 2014]). Infants, Children, and Adolescents: IM: 1.1 mg/kg/dose; maximum dose: 100 mg/dose.Anxiety: Note: Although FDA approved for use in anxiety, data in pediatric patients are sparse; expert recommendations for pediatric patients do not consider hydroxyzine a therapeutic option for the management of anxiety disorders (eg, generalized anxiety disorder, separation anxiety, specific phobias, panic disorder, PTSD); use has generally been replaced by newer, more effective agents (AACAP [Connolly 2007]; Bushnell 2018; Gale 2016)Children and Adolescents: Oral: 0.5 mg/kg/dose every 6 hours; maximum dose is age-dependent: Age Note: In pediatric patients, some experts have recommended lower initial doses, although reported experience is lacking. In adults, experts suggest a lower daily dosing regimen of 37.5 to 75 mg/day in divided doses (WFSBP [Bandelow 2008]; WFSBP [Bandelow 2012]).Pruritus; associated with allergic conditions or chronic urticaria: Children and Adolescents:Age-directed dosing:Children
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